After insertion of the Mirena IUD , I had 2 months of mood swings ( PMS- like symptoms ) then it subsided somewhat for about 2 months . As this was happening my periods became lighter and lighter till they went away all together . Around the same time my periods stopped, my symptoms become worse. I was still having PMS like symptoms (irritability, cranky, depression) every 3 weeks, or so then it increased to every 2 weeks, then I felt like I was constantly PMS ing . Then I started having FLU like symptoms, joint pain, back pain. My arms felt ache all the time for 2 weeks straight. Then all of a sudden I started getting severe leg cramps. My left eye even started twitching … Then I realized I had felt “normal” prior to the Mirena IUD placed .. I had the Mirena removed about 3 days ago , and I still feel hormonal… I can tell some improvement.. no more eye twitching, no more leg cramps , no more ache arms,… Wow .. I wouldn’t have gotten this if I was told these possible side effects